Solid tumors
Testicular seminoma
Testicular seminoma is a germ-cell cancer that usually responds well to treatment. Pure seminoma is managed differently from nonseminomatous or mixed germ-cell tumors, so pathology and tumor markers matter.
Other names and abbreviations
seminoma · germinoma of the testis · testicular germ cell cancer · Seminoma of the testis · classical seminoma
Where transplant fits
Selected relapsed or refractory seminoma may be treated with high-dose chemotherapy and autologous stem cell rescue. It uses the patient’s own cells. It is not a routine first-line procedure and does not usually require a marrow registry donor.
Treatment depends on the exact diagnosis, disease stage, prior treatment and the person’s health. These categories are not estimates of donor demand.
Treatment at a glance
- Who it affects
- Seminoma mainly affects adults, often in younger and middle adult years.
- Other treatment options
- Treatment commonly involves testicular surgery followed by stage-appropriate surveillance, chemotherapy or selected radiotherapy. Relapsed disease needs a salvage plan based on previous treatment and current disease extent.
- Cells used for transplantation
- The patient’s own collected blood-forming cells for autologous stem cell rescue, when that procedure is appropriate.
Questions to bring to your care team
What is the exact diagnosis or subtype? What is the goal of each treatment option? If transplant is being considered, why does it fit this situation, which cells would be used and what are the alternatives?
Sources and further reading
- Testicular Cancer Treatment (PDQ)
NCI · Accessed 2026-09-05 - Indications for haematopoietic cell transplantation and CAR-T: 2025 EBMT practice recommendations
EBMT / Bone Marrow Transplantation · Accessed 2026-09-05 - Stem Cell and Bone Marrow Transplants for Cancer
NCI · Accessed 2026-09-05
Understanding can become action.
Some patients need a blood stem cell donor. Others receive different treatment. Wherever your interest began, you can help JBF reach more people who may be able to donate.
Explore the official registry serving where you live. It explains who can join, how registration works and what donation involves.
Find your official registryIf joining is not right for you, a gift to the Jada Bascom Foundation supports education, outreach and referrals to official registries.
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