Solid tumors
Pineoblastoma
Pineoblastoma is a rare aggressive tumor of the pineal region of the brain. It can obstruct cerebrospinal fluid and spread within the central nervous system. Molecular subtype and age influence treatment and prognosis.
Other names and abbreviations
pinealoblastoma · pineal PNET · primitive neuroectodermal tumor of the pineal region · Pinealoblastoma · previously grouped with CNS primitive neuroectodermal tumours
Where transplant fits
Autologous stem cell rescue is used in selected intensive chemotherapy protocols, particularly in young children or recurrent disease. It supports marrow recovery using the patient’s own cells; a registry donor is not normally part of treatment.
Treatment depends on the exact diagnosis, disease stage, prior treatment and the person’s health. These categories are not estimates of donor demand.
Treatment at a glance
- Who it affects
- Pineoblastoma mainly affects children, with age patterns varying by molecular subtype.
- Other treatment options
- Treatment generally combines surgery, chemotherapy and age-appropriate radiation. Very young children may receive chemotherapy approaches intended to delay radiation, and some protocols use high-dose chemotherapy.
- Cells used for transplantation
- The patient’s own collected blood-forming cells for autologous stem cell rescue, when that procedure is appropriate.
Questions to bring to your care team
What is the exact diagnosis or subtype? What is the goal of each treatment option? If transplant is being considered, why does it fit this situation, which cells would be used and what are the alternatives?
Sources and further reading
- Childhood Medulloblastoma and Other CNS Embryonal Tumors Treatment (PDQ)
NCI · Accessed 2026-09-05 - Indications for haematopoietic cell transplantation and CAR-T: 2025 EBMT practice recommendations
EBMT / Bone Marrow Transplantation · Accessed 2026-09-05 - Stem Cell and Bone Marrow Transplants for Cancer
NCI · Accessed 2026-09-05
Understanding can become action.
Some patients need a blood stem cell donor. Others receive different treatment. Wherever your interest began, you can help JBF reach more people who may be able to donate.
Explore the official registry serving where you live. It explains who can join, how registration works and what donation involves.
Find your official registryIf joining is not right for you, a gift to the Jada Bascom Foundation supports education, outreach and referrals to official registries.
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